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Possible withdrawal symptoms from semaglutide can occur as a result of decreased GLP-1 activity
placebo in the PIONEER 6 trial
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Discussion GLP-1RAs have changed the therapeutic paradigm of T2D as they significantly improve glucose control, also contributing to pleiotropic effects, especially at the cardiovascular level ( Herein we examined the role of GLP-1RAs and the novel dual GIP/GLP-1RA TZP as an add-on to basal insulin therapy compared to basal insulin alone in improving glucose control
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